Key clinical point: Diet quality is not associated with the risk for late-onset multiple sclerosis (MS) in middle-aged individuals.
Major finding: Diet quality, assessed by means of the Alternative Healthy Eating Index-2010, was not statistically significantly associated with late-onset MS diagnosis risk (hazard ratio highest vs. lowest tertile, 0.79; test for trend: P = .22). Smoking did not modify the association.
Study details: Prospective cohort study based on the Danish cohort “Diet, Cancer and Health” evaluated the association between diet quality and the hazards of late-onset MS diagnosis in 56,867 individuals (age, 50-64 years) who were followed for a median of 20.4 years; 124 patients with MS were identified.
Disclosures: This study did not receive any specific funding. The data collection for the Diet, Cancer and Health cohort was funded by the Danish Cancer Society. Ulrik Dalgas has received research support, travel grants, and/or teaching honorary from Biogen Idec, Merck Serono, Novartis, Bayer Schering, and Sanofi Aventis as well as honoraria from serving on scientific advisory boards of Biogen Idec and Genzyme. The other authors reported no conflicts of interest.
Citation: Pommerich UM et al. Mult Scler Relat Disord. 2020 Jan 26. doi: 10.1016/j.msard.2020.101968.