Key clinical point : The personalized multidisciplinary rehabilitation (PMDR) approach can improve highly impacting symptoms in patients with relapse-onset multiple sclerosis (MS) and have a positive influence on their quality of life.
Major finding : Patients receiving PMDR had a reduction in perceived fatigue and improvement of walking abilities and health-related quality of life compared with control individuals. Improved performance on a motor sequence learning task in terms of accuracy was observed after rehabilitation. All improvements persisted at the 4-week follow-up.
Study details : A longitudinal parallel group study included 24 patients with relapse-onset MS, who received a 4-week PMDR, and 24 control individuals.
Disclosures: The study was supported by the Swiss Multiple Sclerosis Society. Athina Papadopoulou, Laura Gaetano, Katrin Parmar, Thierry Ettlin, Corina Schuster-Amft, Jens Wuerfel, Ludwig Kappos, Till Sprenger, and Stefano Magon reported receiving research support/speaker fees/speaker honoraria/travel support/consultancy fees/advisory fees from one or more pharmaceutical companies and/or organizations. The remaining authors declared no conflict of interest.
Citation: Zuber P et al. J Neurol. 2020 Mar 2. doi: 10.1007/s00415-020-09768-6 .