Key clinical point: Sleep fragmentation (defined by low sleep efficiency) is associated with a higher risk of migraine onset on day 1; short sleep duration and low sleep quality are not temporally associated with migraine.
Major finding: Low sleep efficiency was associated with 39% higher odds of headache on day 1. Sleep duration ≤6.5 hours and poor sleep quality were not associated with migraine onset on the day immediately following the sleep period (day 0) and the following day (day 1).
Study details: The data were obtained from a prospective study of 98 adults with episodic migraine.
Disclosures: This study was funded by grants from the National Institute of Neurologic Disorders and Stroke and the American Sleep Medicine Foundation; received financial contributions from Harvard University and its affiliated academic healthcare centers. Dr. Bertisch reported receiving research support from Merck, Sharpe & Dohme and Lockheed Martin and served as a consultant for Verily.
Citation: Bertisch SM et al. Neurology. 2019 Dec 16. doi: 10.1212/WNL.0000000000008740.