Key clinical point: Vitamin D supplementation may decrease the frequency, severity, and duration of migraines.
Major finding: Significantly lower 25 (OH)-vitamin D levels were found in patients with migraine, compared with healthy controls. Migraine patients with low vitamin D levels had a higher incidence of aura, phonophobia/photophobia, autonomic manifestations, allodynia, and medication resistance.
Study details: This was a case-control study of 40 patients with migraine, compared with 40 healthy control patients. Patient history was taken including headache characteristics, MIGSEV, and HIT-6 scores. Each patient’s serum 25 (OH)-vitamin D level was measured.
Citation: Hussein M, et al. J Pain Res. 2019 Aug 20;12:2529-36. doi: 10.2147/JPR.S216314. eCollection 2019.