Migraine Briefs

Osmophobia is a Clinical Marker of Migraine


Osmophobia is a specific clinical marker of migraine, but not tension-type headache, a new study found. Researchers conducted a prospective study on 193 patients suffering from migraine without aura, migraine with aura, episodic tension-type headache, or a combination of these. Each patient was asked to describe in detail osmophobia, when present, in the 4 headache attacks. Among the findings:

  • 45.7% of migraine with aura attacks were associated with osmophobia.
  • 67.2% of patients with migraine reported osmophobia in at least a quarter of the attacks.
  • No tension-type headache attack was associated with osmophobia.

Terrin A, et al. A prospective study on osmophobia in migraine versus tension-type headache in a large series of attacks. [Published online ahead of print September 19, 2019]. Cephalalgia. doi: 10.1177/0333102419877661.

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