Literature Monitor

Is It Possible to Predict Seizures?

Nat Rev Neurol; ePub 2018 Aug 21; Kuhlmann et al


 

Conventional medical wisdom insists that it is not possible to predict the onset of seizures with any certainty, but recent research suggests otherwise, according to a review published in Nature Reviews Neurology.

  • An influential 2007 review of the medical literature concluded that there was insufficient evidence to foresee the onset of seizures.
  • However, an international team of experts summarized several recent advances that suggest seizure prediction may be possible.
  • The new review discusses a small experiment in which intracranial EEGs were used prospectively to predict seizures.
  • Additional advances include EEG databases, seizure prediction competitions, and a better understanding of the mechanism of action behind seizures.

Kuhlmann L, Lehnertz K, Richardson MP, et al. Seizure prediction - ready for a new era. [Published online ahead of print August 21, 2018] Nat Rev Neurol. doi: 10.1038/s41582-018-0055-2

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