Literature Monitor

TLE Responds to Laser Interstitial Therapy

Epilepsy Res; ePub 2017 Oct 27; Bezchlibnyk et al.


Magnetic resonance-guided stereotactic laser amygdalohippocampotomy (SLAH) is emerging as a promising approach for patients with mesial temporal lobe epilepsy according to a recent review of the literature.

  • Laser interstitial thermal therapy that is guided by MRI appears to be a safe, effective way to manage patients with mesial temporal lobe epilepsy—when used in properly selected patients.
  • SLAH is less invasive than anterior temporal lobectomy and allows the surgeon to immediately destroy target tissue, which is not the case with radiosurgery.
  • SLAH also has the advantage of allowing the surgeon to remove larger amounts of tissue than can be done with radiofrequency ablation.
  • Bezchlibnyk et al state that MR-guided laser thermal therapy is less likely to cause neuropsychological deficits, when compared to open surgery.

Bezchlibnyk YB, Willie JT, Gross RE. A neurosurgeon`s view: Laser interstitial thermal therapy of mesial temporal lobe structures. [Published online ahead of print Oct 27 2017] Epilepsy Res.

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