In patients who have had surgical resection of an insular glioma, the wider the extent of the resection, the longer they remain free from seizures, according to a study from the department of neurological surgery at the University of California, San Francisco (UCSF).
- The analysis included 109 patients who had surgery for insular tumors from 1997 to 2015 at UCSF.
- At final follow-up, 42 patients (39%) remained seizure free.
- Increasing the extent of the resection predicted freedom from seizures.
- The analysis also revealed that performing a second resection provided even greater seizure control; 8/22 patients with recurrent seizures no longer had them after the second surgery.
- Patients who experienced a second seizure after resection were more likely to have had tumor progression.
Wang DD, Deng H, Hervey-Jumper SL, Molinaro AA, Chang EF, Berger MS. Seizure outcome after surgical resection of insular glioma. [Published online ahead of print Nov 8, 2017] Neurosurgery. doi: 10.1093/neuros/nyx486.