Literature Monitor

Nocturnal Seizures Linked to Severe Hypoxemia

Hypoxemia from nocturnal seizures may be responsible for an increased risk of SUDEP.


Patients who have seizures while asleep are more likely to experience severe and longer episodes of hypoxemia compared with seizures while awake according to an examination of 48 recorded seizures from 20 adults with epilepsy. The analysis also suggested that an increased risk of sudden death may be caused by hypoxemia from nocturnal seizures.

Latreille V, Abdennadher M, Dworetzky BA et al. Nocturnal seizures are associated with more severe hypoxemia and increased risk of postictal generalized EEG suppression [published online ahead of print July 17, 2017]. Epilepsia. 2017;doi: 10.1111/epi.13841.

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