Literature Monitor

Is Amygdala Enlargement a Unique Feature of Temporal Lobe Epilepsy?

MRIs found it exists in those without epilepsy as well.


 

Although an enlarged amygdala (AE) has been found in patients with temporal lobe epilepsy, a recent analysis found that AE exists among those without epilepsy. The study used high resolution T1-weighted MRI scans and analyzed healthy controls and patients with epilepsy. The investigation revealed that AE was more common in nonlesional localization related epilepsy, when compared with idiopathic generalized epilepsy and healthy controls.

Reyes A, Thesen R, Kuzniecky R, et al. Amygdala enlargement: temporal lobe epilepsy subtype or nonspecific finding? Epilepsy Res. 2017;132:34-40.

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