Literature Review

Can measures help predict neurocognitive outcomes following ATL?

Investigators examine rsFC graph-theory measures



Researchers examined 32 patients with temporal lobe epilepsy (TLE) who underwent anterior temporal lobectomy (ATL). Patients underwent pre-and postsurgery neuropsychological functional testing. The study found that presurgery resting-state functional connectivity (rsFC) graph-theory measures can help predict neurocognitive outcomes after ATL. The integration measure was the most predictive of neurocognitive outcomes while segregation measure was the least predictive.

Doucet GE, Rider R, Taylor N, et al. Presurgery resting-state local graph-theory measures predict neurocognitive outcomes after brain surgery in temporal lobe epilepsy. Epilepsia. 2015;56(4):517-526.

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