The Authors Reply, “The Weekend Effect in Hospitalized Patients”

We would like to thank Drs. Flansbaum and Sheehy for their interest in our article.¹ We appreciate their mentioning the highly publicized disputes and additional manuscripts^2,3 that were published after our literature review, which was conducted in 2013.

As discussed by Drs. Flansbaum and Sheehy and the editorial accompanying our article,⁴ the precise contributions, if any, of various potential factors (eg, patient characteristics, resources, workforce) to the development of the weekend effect is uncertain at this time; although, as mentioned by Drs. Flansbaum and Sheehy, more recent work^2,3 suggests that patient characteristics may be a more important determinant on outcomes.

Despite the uncertainty surrounding the exact composition and contributions of various elements to the weekend effect, it does appear to be a real phenomenon, as noted by the editorialists.⁴ We hope that our manuscript encourages future investigators to help elucidate the nature of the input contributing to the weekend effect.