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Fourth approved indication for ofatumumab in chronic lymphocytic leukemia

The Journal of Community and Supportive Oncology. 2016 November;14(11):447-449 | 10.12788/ jcso.0303

The recent decision by the US Food and Drug Administration to approve ofatumumab in combination with fludarabine and cyclophosphamide in relapsed disease marks a fourth approved indication for this drug in patients with chronic lymphocytic leukemia (CLL). Ofatumumab is a fully human monoclonal antibody that targets the CD20 protein on the surface of B cells, first approved for the treatment of CLL back in 2009.

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