A novel treatment approach prolonging survival in an uncommon metastatic primary bladder adenocarcinoma

Primary bladder adenocarcinoma  is an epithelial malignancy with pure glandular differentiation, without evidence of typical urothelial (transitional cell) carcinoma. PBA is rare, accounting for 0.5%-2% of all malignant bladder neoplasms, and it is seen more frequently in men than in women and is commonly diagnosed in the sixth decade of life.^1-3 Clinical presentation includes hematuria and symptoms of bladder irritation.²

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