African American patients with mycosis fungoides (MF) demonstrated poorer survival than white patients after accounting for disease characteristics, socioeconomic factors, and types of treatment, warranting further investigation into the underlying biology of MF and prescribed treatment modalities, according to a recent study. The US National Cancer Database was used to identify patients with histologically confirmed MF from 2004 to 2014. Clinicopathologic, socioeconomic, and treatment data were compared among the races by using the chi-square test. Overall survival was evaluated by using the log-rank test, multivariable Cox proportional hazard regression, and propensity score-matched analysis. Researchers found:
- Of 4,459 patients with MF, 77.7% were white, 19.2% were African American, and 3.2% were Asian.
- Older age, treatment received in a community facility, government insurance, higher Charlson-Deyo score, male sex, higher clinical stage, receipt of radiotherapy or chemotherapy, and African American race were predictors of poor overall survival on multivariate analysis, whereas Asian race trended toward improved outcomes.
Su C, Nguyen KA, Bai HX, et al. Racial disparity in mycosis fungoides: An analysis of 4495 cases from the US National Cancer Database. [Published online ahead of print June 20, 2017]. J Am Acad Dermatol. doi:10.1016/j.jaad.2017.04.1137.
This Week's Must Reads
Nevus Development Trajectory from Age 3 to 16 Years, JAMA Dermatology; ePub 2018 Sep 12; Asdigian, et al
Pruritis Strongly Associated with Certain Cancers , J Am Acad Dermatol; ePub 2018 Sep 11; Larson, et al
Trends in Medicare Billing Among Mohs Surgeons, Dermatolog Surg; ePub 2018 Sep 7; Tsai, et al
Mohs Surgery Effective for Invasive Melanomas, Dermatolog Surg; ePub 2018 Sep 7; Degesys, et al
Young Adults with Psoriasis Have Impaired QOL, J Dermatolog Treat; ePub 2018 Sep 7; Bronckers, et al
Must Reads in Medical Dermatology
Incidence of Skin Diseases by Age Group Examined, Int J Dermatol; 2018 Sep; Wessman, et al
Disparities in Dermatologist Density Found in US , JAMA Dermatology; ePub 2018 Sep 5; Feng, et al
Hospital Readmissions for Skin Disease Evaluated, J Am Acad Dermatol; ePub 2018 Aug 22; Arnold, et al
Should Medical Coding Be Taught During Residency?, J Drugs Dermatol; 2018 Jun; Blecher, Halverstam, et al
Use of UV Radiation for Medical, Cosmetic Purposes, J Clin Aesthet Dermatol; 2018 Feb; Sampson, et al