Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Age and Hydration Play Roles in Skin Firmness

J Cosmet Dermatol; ePub 2017 Dec 27; Mayrovitz, et al

Experimental finding show clear differences in skin firmness between age-groups, with skin hydration playing a minor role, according to a recent study. Skin firmness was quantified using handheld devices that measure the force to indent skin 0.3 and 1.3 mm (F0.3 and F1.3). Skin hydration was quantified using handheld devices that measured tissue dielectric constant (TDC) at 300 MHz to skin depths of 0.5 and 2.0-2.5 mm. All parameters were measured bilaterally in the jowl area and volar forearm of 60 women grouped by age <45 years (YOUNG) and ≥45 years old (MATURE). Researchers found:

  • All measured parameters were bilaterally symmetrical at jowl and forearm.
  • Forearm and jowl indentation forces were greater in YOUNG with statistically significant declines with advancing age with regression relations most evident at shallower indentation depths.
  • Quantitative relations for arm and jowl were F0.3 = 0.256 × AGE + 32.7 mN and F 0.3 = −0.07 × AGE + 17.7 mN.

Mayrovitz HN, Wong J, Fasen M. Age and hydration dependence of jowl and forearm skin firmness in young and mature women. [Published online ahead of print December 27, 2017]. J Cosmet Dermatol. doi:10.1111/jocd.12477.

This Week's Must Reads

Dermatologist-Delivered Intervention Is Effective, JAMA Dermatology; ePub 2018 Aug 8; Mallett, et al

HRQOL in Patients with Cutaneous T-Cell Lymphoma, Int J Dermatol; ePub 2018 Aug 3; Holahan, Farah, et al

Disparities Seen in Access to Injectable Biologics , J Dermatolog Treat; ePub 2018 Aug 4; Feng, et al

Psoriasis Not Associated with Higher Dementia Risk, J Am Acad Dermatol; ePub 2018 Aug 6; Pezzolo, et al

Discerning Merkel Cell Carcinoma from Other Tumors, Am J Dermapathol; ePub 2018 Jul 24; Bandino, et al

Must Reads in Aesthetic Dermatology

FDA Approves Restylane Lyft for Back of Hands, FirstWord Pharma news release; 2018 May 21

Darker Skin and Side Effects of Chemical Peels, J Am Acad Dermatol; ePub 2018 Mar 5; Vemula, et al

Absorbable Suture Suspension Proves Effective, Aesthet Surg J; ePub 2017 Dec 8; Ogilvie, et al

Age and Hydration Play Roles in Skin Firmness, J Cosmet Dermatol; ePub 2017 Dec 27; Mayrovitz, et al

FDA Clears CoolSculpting for Double Chin Treatment, Allergan plc news release; 2017 Dec 12