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Malignant Melanoma: Advances in Diagnosis, Prognosis, and Treatment

Advances in therapy allow new hope for patients with metastatic and potentially nodal disease as well, but cure remains elusive.
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Michael Krathen, MD

The detection of cutaneous melanoma still largely relies on clinical suspicion, skin biopsy, and histopathologic evaluation. New technologies are being evaluated to bypass the skin biopsy in the detection of melanoma. The quest for reliable biomarkers, with respect to subclinical detection, prognosis, and predicting treatment response, is longstanding and ongoing. New therapies have been developed for metastatic disease, including targeted small molecule inhibitors as well as immune modulators.

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