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Topical Therapy With Tretinoin and Ammonium Lactate for Acanthosis Nigricans Associated With Obesity

Cutis. 2003 January;71(1):33-34
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Acanthosis nigricans (AN) is a cutaneous marker of various underlying systemic conditions. To date, no satisfactory topical therapy for this cutaneous disorder has been described. The following is a report of the successful use of a combination of 12% ammonium lactate cream and 0.05% tretinoin cream to treat AN associated with obesity.