Spiculated morphology and antiparallel orientation on ultrasound may predict poor prognosis in breast cancer

Key clinical point: Sonography features, such as spiculated morphology and antiparallel orientation, were significantly associated with worsened survival outcomes in patients with primary breast cancer (BC; tumor size <20 mm).

Major finding: The presence of spiculated morphology and antiparallel orientation on ultrasound was a significant risk factor for poor breast cancer-specific survival (hazard ratio [HR] 7.45; P < .001) and disease-free survival (HR 6.42; P < .001), with age ≥55 years (P < .05) and positive lymph node metastases (P < .001) also being associated with worse prognosis.

Study details: Findings are from a retrospective study including 790 women with small primary BC (tumor size <20 mm).

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Disclosures: This study was supported by the National Natural Science Foundation of China and other sources. The authors declared no conflicts of interest.

Source: Shao S et al. Ultrasound features for prediction of long-term outcomes of women with primary breast cancer <20 mm. Front Oncol. 2023;13:1103397 (Mar 16). Doi: 10.3389/fonc.2023.1103397