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Phialophora verrucosa as a Cause of Deep Infection Following Total Knee Arthroplasty

The American Journal of Orthopedics. 2013 November;42(11):515-518
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Deep joint infection is one of the most feared complications following total joint replacement. Prompt diagnosis and treatment with 2-staged revision is currently the gold standard for treatment. We report a case of a chronic infection following total knee replacement caused by Phialophora verrucosa, a form of dematiaceous fungus. The patient was treated with an antibiotic spacer and a course of oral anti-fungal agents. To our knowledge, there have been no reported cases of P verrucosa as a cause of infection in hip or knee arthroplasty.