Xian Wen Jin, MD, PhD Department of General Internal Medicine, The Cleveland Clinic
Craig Nielsen, MD Department of General Internal Medicine, The Cleveland Clinic
Jennifer Brainard, MD Department of Anatomical Pathology, The Cleveland Clinic
Belinda Yen-Lieberman, PhD Department of Clinical Pathology, The Cleveland Clinic
Address: Xian Wen Jin, MD, PhD, Department of General Internal Medicine, S70, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: jinx@ccf.org
ABSTRACTNew advances in Papanicolaou test technology, human papillomavirus DNA testing, and revisions in the Bethesda terminology for cervical cytology have transformed the management of abnormal Pap tests. This approach has been validated by a recent randomized clinical trial, and in some instances can reduce the number of colposcopies by 50%.