Acute Kidney Injury in the ICU: Medication Dosing
In ICUs throughout the world, acute kidney injury (AKI) is becoming increasingly common. Even when the admitting complaint is straightforward, a hospitalized kidney patient can develop significant complications and require ongoing adjustments in care, as seen in these reader questions. Care of the critically ill patient is never static, and hospital clinicians are advised to keep abreast of the current literature and seek advice from other health professionals.
9. Coca SG, Yusuf B, Shlipak MG, et al. Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis. 2009;53:961-973.
10. Matzke GR, Aronoff GR, Atkinson AJ Jr, et al. Drug dosing consideration in patients with acute and chronic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2011;80:1122-1137.
11. Vilay AM, Churchwell MD, Mueller BA. Clinical review: drug metabolism and nonrenal clearance in acute kidney injury. Crit Care. 2008;12:235.
