Cleveland Clinic Journal of Medicine (CCJM) is an indexed, peer-reviewed journal published monthly by Cleveland Clinic as part of its program of medical education. The Journal is designed to meet the continuing medical education needs of general internists, cardiologists, and other medical subspecialists by providing practical information on new developments in the diagnosis and treatment of patients encountered in daily practice. CME credits are offered for several articles in each issue.

CCJM does not accept original research or standard case reports. For more information on the type and format of specific series, see Author Information.

Selection of Topics

Topics should be of interest to practicing internists. Before submitting a manuscript, please contact CCJM editorial staff to make sure the topic fits the Journal's mission, and to make sure that a similar article is not already under consideration.

Submission of Manuscripts

Articles should be submitted via CCJM's online manuscript submission and peer-review system ( A tutorial on how to use the system is available, but questions can also be sent to or 216-444-2661.

Authorship by Residents and Fellows

Medical students, residents, and fellows may submit articles and may be listed as first author. However, CCJM policy requires that a senior physician mentor the junior author and be listed as a co-author.

Participation of Pharmaceutical and Medical Education Companies

CCJM does not accept articles written by authors who are employed by pharmaceutical companies, or papers prepared by medical education companies whose work is funded by pharmaceutical companies. For a detailed explanation of this policy, please see: "New CCJM policy: No manufacturer involvement in the preparation of articles."

Avoiding Perception of Bias

We ask all authors to ensure that articles are not biased, are fair and balanced, and are based on the best available evidence. Opinions can be offered, but should be clearly defined (and referenced) as to whether they are based on clinical experience or published evidence.

When preparing your article, we ask that you adhere to the following guidelines:

  • There should not be bias toward any product, procedure, device, or therapy.
  • All applicable products, devices, or therapies should be addressed in your article to ensure fairness and balance.
  • Classes of drugs and devices should be used rather than individual agents where appropriate.
  • When applicable, discussion of cost considerations should be included.

Avoiding Plagiarism

To ensure the integrity and originality of the content of submitted manuscripts, CCJM uses software to detect plagiarism, including cutting-and-pasting and self-plagiarism. Authors should provide full attribution for any information borrowed from other sources. For additional guidance, please watch our 15-minute video, Avoiding Plagiarism.

Discussion of Off-Label Use or Investigational Products

When an unlabeled use of a commercial product or an investigational use not yet approved by the US Food and Drug Administration (FDA) is discussed in an article, please disclose that the product is not labeled for the use under discussion or that the product is investigational and not yet approved by the FDA.

Cover Letter

Include a cover letter with the full name, address, telephone number, e-mail address, and fax number of the corresponding author. Authors will be sent a financial relationship disclosure form after the paper is submitted; but if there are any special issues, please alert the editors in your cover letter.

Manuscript Preparation

Title Page: The title page should include all authors, their institutional affiliations, academic titles, and contact information.

Formatting: Text should be typed and double spaced, in 12-point type. Although a variety of formats are acceptable, Microsoft Word is preferred. Please note that tables and figures should not be embedded in the text of the article.

References: No more than 40 references should be included, and references to textbooks should be avoided. Number references in the order in which they are cited in the text. Follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals ( Abbreviate periodicals according to Index Medicus. If a citation has 6 or fewer authors, list all 6 authors; if a citation has 7 or more authors, list the first 3, then "et al." Authors are responsible for the accuracy of references.

Tables and Figures: Tables and figures should not be embedded in the text of the article. Where photographs of patients are included, consent to publish the photograph, signed by the patient, must accompany the manuscript. Drawings, graphs, and charts should be professionally rendered. For detailed instructions regarding format and resolution, see Tables, Figures, and Digital Images.

Copyright permissions for tables and figures previously published: If a table or figure has been published elsewhere, provide a permission letter (for both print and electronic publication) from the publisher, even if it is from the author's own work.

Peer Review

All manuscripts undergo peer review, usually by 3 reviewers, including at least 1 content expert and 1 general internist. Manuscripts are reviewed for content, perception of bias, and educational impact on our readership. Authors are usually notified within 8 weeks about the acceptability of a manuscript, but longer intervals are sometimes unavoidable.

Editing and Galley Proofs

All papers accepted for publication will be edited to conform to CCJM's editorial style. Authors are responsible for all statements made in their work, including any changes made by CCJM editors. Copyright ownership must be transferred to the publisher. An appropriate form will be supplied.