Chronic hepatitis B virus infection: Issues in treatment
Robert O’Shea, MD
Department of Gastroenterology and Hepatology, Cleveland Clinic
Address: Robert O’Shea, MD, Department of Gastroenterology and Hepatology, A30, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: firstname.lastname@example.org
Medical Grand Rounds articles are based on edited transcripts from the Division of Medicine Grand Rounds presentations at Cleveland Clinic. They are approved by the author but are not peer-reviewed.
The author indicates that he received a salary from sanofi-aventis and enGene corporations for research support.
ABSTRACTAs research continues to define the optimal management of chronic hepatitis B virus (HBV) infection, clinicians must deal with a number of yet unresolved issues: Should we treat all patients with HBV infection to prevent liver cancer, even if they have no evidence of active disease? Which is the best treatment strategy? What do we do with patients who develop resistance to our current drugs? Should we treat patients with HBV infection who have already developed cirrhosis?