Managing genital herpes infections in pregnancy
Carolyn Gardella, MD, MPH
Assistant Professor, University of Washington, Department of Obstetrics and Gynecology, Division of Women’s Health, Seattle
Zane A. Brown, MD
Professor, University of Washington, Department of Obstetrics and Gynecology, Division of Perinatology, Seattle
Address: Carolyn Gardella, MD, MPH, Department of Obstetrics and Gynecology, University of Washington Medical Center, Box 356460, Seattle, WA 98195-6460; e-mail: email@example.com
Both authors are on the speakers’ bureau for GlaxoSmithKline. Their work is supported in part by the National Institute of Allergy and Infectious Diseases under grant AI-30731.
ABSTRACTGenital herpes is common and is becoming more so, with a seroprevalence of 25% in middle class primary care settings. Primary genital herpes in pregnancy most often is subclinical, but it also can cause severe illness. Further, active genital herpes at the time of vaginal delivery poses significant risk of neonatal infection, especially if the mother acquired the infection in the third trimester. It is important to prevent genital herpes acquisition in pregnancy and to diagnose recurrent genital herpes to prevent neonatal herpes.