William C. McBee Jr., MD Department of Obstetrics and Gynecology, MetroHealth Medical Center; Department of Obstetrics and Gynecology, Cleveland Clinic
Pedro F. Escobar, MD Section of Gynecologic Oncology and Department of Obstetrics and Gynecology, Cleveland Clinic
Tommaso Falcone, MD Chairman, Department of Obstetrics and Gynecology, Cleveland Clinic; Professor of Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH
Address: Tommaso Falcone, MD, Department of Obstetrics and Gynecology, A81, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: falcont@ccf.org
ABSTRACTOvarian cancer is deadly if not detected early, but it is only one of many causes of pelvic masses, which are common. The physician's job is to determine if a mass is likely to be malignant and needing surgical evaluation. The best predictors of malignancy are a combination of factors that include the patient's age, family history, menopausal status, symptoms, findings on physical examination and imaging studies, and blood level of the cancer biomarker CA125.