The effect of obstructive sleep apnea on chronic medical disorders
Nancy Collop, MD
Associate professor of Medicine, Division of Pulmonary/Critical Care Medicine, Director, Sleep Disorder Center, Johns Hopkins University, Baltimore, MD; President, American Board of Sleep Medicine
Address: Nancy Collop, MD, Division of Pulmonary/Critical Care Medicine, Johns Hopkins University, 1830 East Monument St, Room 555, Baltimore, MD 21205; e-mail: email@example.com
Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at Cleveland Clinic. They are approved by the author but are not peer-reviewed.
Dr. Collop has indicated that she serves as a consultant for Sleep Services of America and has received grant support from Sepracor.
ABSTRACTEvidence is mounting that obstructive sleep apnea causes or contributes to many chronic medical diseases, and that treatment with continuous positive airway pressure (CPAP) often improves concomitant diseases. The author reviews the association of obstructive sleep apnea with arterial hypertension, pulmonary hypertension, stroke, coronary artery disease, heart failure, sudden death, gastroesophageal reflux disease, and diabetes mellitus.