Current Drug Therapy

Exenatide and pramlintide: New glucose-lowering agents for treating diabetes mellitus

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ABSTRACTInsulin is not the only hormone that regulates plasma glucose levels. Glucagon-like peptide 1 (GLP-1), produced in the small intestine, and amylin, produced by beta cells in the pancreas, also have glucose-lowering effects. Synthetic analogues of these hormones are now available for clinical use.


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