Evaluating and managing hypogammaglobulinemia
Mark E. Rose, MD
Section of Adult Allergy and Immunology, Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation
David M. Lang, MD
Head, Section of Adult Department of Allergy and Immunology, Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation
Address: David M. Lang, MD, Department of Allergy and Immunology, C22, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195
Dr. Lang has indicated that he has received honoraria from, has served as a consultant for, or has carried out clinical research with the AstraZeneca, Aventis, Genetech, GlaxoSmithKline, Ivax, Merck, Novartis, Pfizer, and Schering/Key corporations.
ABSTRACTIf a patient has frequent or recurrent bronchopulmonary or sinus infections, they may be due to low levels of immunoglobulins. This article describes common primary (idiopathic) and secondary forms of hypogammaglobulinemia and how to evaluate and manage them.