Medical Grand Rounds

Treating depression in a mother of five: What to do when the first step fails

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ABSTRACTWhat should one do with a depressed patient who does not get better? If depression does not respond to an antidepressant given in adequate doses for an adequate time, logical next steps include increasing the dose, adding a different medication, or adding a nonpharmacologic therapy. Or one can reconsider the diagnosis.


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