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Safety of statins: Effects on muscle and the liver

Cleveland Clinic Journal of Medicine. 2005 November;72(11):990-993, 996-1001
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ABSTRACTAlthough statin drugs can have adverse effects on muscles and the liver, these effects are uncommon. Caution is warranted in patients at higher risk, ie, those who are elderly, frail, or small; have multisystem disease; are receiving immunosuppressive drugs or other medications that interact with statins; or are receiving higher doses of a statin.