Extraesophageal symptoms of GERD
Kenneth R. DeVault, MD
Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Fla
Correspondence: Kenneth R. DeVault, MD, Director of Gastrointestinal Research, Division of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224
Gastroesophageal reflux disease (GERD) can be the primary cause of, or an aggravating contributor to, a wide variety of conditions affecting extraesophageal structures. As a result, GERD can lead to a number of pulmonary symptoms and diseases, otolaryngologic findings and symptoms, and other extraesophageal manifestations, including dental erosions. Clinicians must be aware of the possibility of these extraesophageal reflux-related conditions, even in the absence of classic esophageal symptoms of GERD. While antireflux therapy is often helpful, response to treatment is less predictable than it is for typical GERD.