Wendy Armstrong, MD Department of Infectious Disease, The Cleveland Clinic
Leonard Calabrese, DO Section Head, Clinical Immunology, Department of Rheumatic and Immunologic Disease, The Cleveland Clinic
Alan Taege, MD Department of Infectious Disease, The Cleveland Clinic
Address: Wendy Armstrong, MD, Department of Infectious Disease, S32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: armstrw@ccf.org
Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the authors but are not peer-reviewed.
This paper discusses treatments that are not approved by the US Food and Drug Administration for the use under discussion.
ABSTRACTThe recommendation for HIV antiretroviral therapy is changing from "treat early, treat hard" to "treat a little later, treat hard" as more toxicities of the drugs are recognized. Drug-resistant HIV is becoming a serious problem, even in treatment-naive patients. For HIV patients with organ failure, transplantation is increasingly an option.
