Sandra G. Adams, MD Department of Medicine, Division of Pulmonary Medicine and Critical Care Medicine, the University of Texas Health Science Center at San Antonio, and the South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division
Antonio Anzueto, MD Department of Medicine, Division of Pulmonary Medicine and Critical Care Medicine, the University of Texas Health Science Center at San Antonio, and the South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division
Address: Antonio Anzueto, MD, The South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, Pulmonary Disease Section (711E), 7400 Merton Minter Boulevard, San Antonio, TX 78284, anzueto@uthscsa.edu
Dr. Anzueto has received grant support from SmithKline Beecham Pharmaeuticals, Eli Lilly & Connpany, and Introbiotics.
ABSTRACT
Antibiotics can be effective against acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease, but with bacterial resistance to multiple antibiotics increasing worldwide, appropriate antibiotic selection is critical. Categorizing patients with acute exacerbations according to age, number of exacerbations per year, disease severity, degree of pulmonary impairment, and presence of comorbid conditions helps to direct therapy.