Aspirin, ticlopidine, and clopidogrel in acute coronary syndromes: Underused treatments could save thousands of lives
Walter A. Tan, MD, MS
Section of Interventional Radiology, Pittsburgh Vascular Institute, University of Pittsburgh Medical Center-Shadyside, Pittsburgh
David J. Moliterno, MD
Medical Director, Angiographic Core Laboratory, Department of Cardiology, Cleveland Clinic
Address: David J. Moliterno, MD, Department of Cardiology, F25, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; email@example.com
Aspirin is the cornerstone of therapy for unstable angina and acute myocardial infarction and the foundation on which other therapies are added, both in the short term and the long term. Yet, despite clear data, aspirin is woefully underused or is often used late. Prompt administration of aspirin could save thousands of lives each year. Ticlopidine and clopidogrel have a synergistic effect when used with aspirin, and can also have a role in treating patients who are aspirin-resistant or have diffuse atherosclerosis.