Antileukotrienes and asthma: Alternative or adjunct to inhaled steroids?
Mani S. Kavuru, MD
Director, Pulmonary Function Laboratory, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic
Revathi Subramony, RPH
Staff Pharmacist, Metrohealth Medical Center, Cleveland
Ana R. Vann, PharmD
Drug Information Clinical Pharmacist, Department of Pharmacy, Cleveland Clinic
Address: Mani S. Kavuru, MD, Department of Pulmonary and Critical Care Medicine, A90, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195
Antileukotriene agents may be reasonable and safe alternatives or adjuncts to inhaled steroid therapy in chronic asthma, as they act at sites further down in the inflammatory cascade. This article reviews the clinical experience with three antileukotriene agents and discusses their role in the management of asthma.