The role of azole antifungal agents for systemic antifungal therapy
YU-PING LEE, PharmD
Dr. Lee is a pharmacy resident at the Cleveland Clinic, specializing in infectious disease.
MORTON GOLDMAN, PharmD
Dr. Goldman is the pharmaceutical care clinical manager in the Department of Pharmacy at the Cleveland Clinic.
DONALD G. VIDT, MD
Although amphotericin B remains the cornerstone of antifungal drug therapy, fluconazole and itraconazole have been found useful for long-term maintenance or prophylactic regimens. This article reviews characteristics of fluconazole and itraconazole and compares them with ketoconazole and amphotericin B.