Current issues in menopausal hormone replacement therapy
HOLLY L. THACKER, MD
Dr. Thacker is a staff member of the departments of General Internal Medicine and Gynecology and Obstetrics and associate director of the Menopause Center at the Cleveland Clinic, and an assistant professor of Internal medicine at Ohio State University.
DONALD G. VIDT, MD
For most menopausal women, the benefits of hormone replacement therapy outweigh the risks, despite the fears aroused by the unproven link to breast cancer. If the goal is solely to relieve menopausal symptoms, the treatment duration is generally 2 to 3 years and then gradually tapered off. If the goal is to provide cardiac protection and prevent osteoporosis, long-term, possibly lifetime, treatment is needed.