Left ventricular hypertrophy and cardiovascular prognosis
Michael S. Lauer, MDAddress reprint requests to M.S.L., Department of Cardiology. F15, The Cleveland Clinic Foundation. 9500 Euclid Avenue, Cleveland, OH 44195.
Left ventricular hypertrophy is an important independent predictor of cardiovascular risk. The therapeutic implications of this remain to he explored.KEY POINTS
Electrocardiographic left ventricular hypertrophy has long been known to be a risk factor for adverse cardiovascular events; however, electrocardiography is not very sensitive for detecting this condition. More recently, echocardiography has been found to provide a more accurate and sensitive estimation of left ventricular mass than electrocardiography does. Both electrocardiographic and echocardiography left ventricular hypertrophy independently predict a higher risk of coronary artery disease, cardiovascular disease, and total mortality. These associations have been noted in the general population, in patients with hypertension, and in patients undergoing coronary angiography. Important clinical correlates of left ventricular hypertrophy include hypertension, obesity, genetic predisposition, and. possibly, advanced age.