Systemic diseases associated with intermediate uveitis
Steven A. Boskovich, MD
Careen Y. Lowder, MD, PhDAddress reprint requests to C.Y.L., Department of Ophthalmology, A31, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195.
David M. Meisler, MD
Froncie A. Gutman, MD
Intermediate uveitis is characterized by vitreal inflammation with associated inflammation of the vitreous base and peripheral anterior retina and choroid. It may be found as an isolated and idiopathic condition or in association with systemic disorders such as multiple sclerosis and sarcoidosis.OBJECTIVE
To identify the clinical features of intermediate uveitis and assess its association with systemic diseases.METHODS
Retrospective study of 83 patients presenting with intermediate uveitis between 1970 and 1991.RESULTS
Evidence of systemic disorders was found in 26 of 83 patients (31.3%). Of these 26 patients, 10 had presumed sarcoidosis, 6 had multiple sclerosis, 2 had isolated optic neuritis, 2 had inflammatory bowel disease, 4 had isolated thyroid abnormalities, and 2 had histories suggestive of Epstein-Barr virus infection. Associated ocular findings included cystoid macular edema, peripheral retinal perivascular sheathing, cataracts, posterior vitreous detachment, fine keratic precipitates, preretinal macular fibrosis, retinal tears, retinal detachment, and optic disc edema.CONCLUSIONS
Patients with intermediate uveitis may have associated systemic diseases and should have careful follow-up with regular systemic evaluation.