Diabetic ketoacidosis associated with pheochromocytoma
Elazer R. Edelman, MD, PhDAddress reprint requests to E.R.E., Cardiovascular Division, Department of Internal Medicine, Brigham and Women’s Hospital, Boston, MA 02115.
Cynthia A. Stuenkel, MD
John D. Rutherford, MB, BCh
Gordon H. Williams, MD
A 29-year-old woman was found to have diabetic ketoacidosis associated with classic findings of pheochromocytoma, an association previously undescribed. The patient also had a significant insulin requirement that resolved after tumor excision. Pheochromocytoma with associated hyperglycemia and glycosuria has been reported since 1912, but ketoacidosis has been thought not to occur with pheochromocytoma. The findings in this case are described, and glucose metabolism in pheochromocytoma is reviewed.