Pancreas transplantation: state of the art
Byron J. Hoogwerf, MD
Sharon Grundfest-Broniatowski, MDAddress reprint requests to S.G.-B., head, Section of Pancreas Transplantation, Department of General Surgery, Desk A110, The Cleveland Clinic Foundation, One Clinic Center, 9500 Euclid Avenue, Cleveland, Ohio 44195-5043.
Improvements in technique and in the diagnosis of rejection have led to progressively better pancreas transplant graft and patient survival rates over the past 5 years. Refinements in organ preservation are making it easier for centers to share organs, with better immunologic matching and therefore additional improvement in results. As new immunosuppressive agents become available, pancreas transplantation may be an option for diabetic patients early in the course of their disease, before secondary complications become disabling.