Estrogen supplements in menopause
Wilma F. Bergfeld, MD, FACP
Geoffrey P. Redmond, MD
Delbert L. Booher, MDAddress reprint requests to D.L.B., Department of Gynecology, The Cleveland Clinic Foundation, One Clinic Center, 9500 Euclid Avenue, Cleveland, Ohio 44195.
The number of women aged 65 and older is expected to double by the year 2000, increasing the need for effective management of symptoms related to menopause. Contemporary management of menopause addresses the continuum of events associated with the effects of estrogen deprivation on quality and duration of life, including neuroendocrine changes, urogenital atrophy, sexual dysfunction, skin and hair changes, osteoporosis, and cardiovascular disease. The risks and benefits of management strategies, including hormone replacement therapy, must be weighed carefully by both physician and patient. The use of estrogens and progestins, alternative compounds, dosages, routes of administration, and their advantages and disadvantages must be analyzed.