Outpatient antibiotic therapy for urinary tract infections in women
Thomas F. Keys, MDAddress reprint requests to Department of Infectious Disease, The Cleveland Clinic Foundation, One Clinic Center, 9500 Euclid Avenue, Cleveland, Ohio 44195.
Culture may not be required to confirm the diagnosis of urinary tract infections in young women with symptoms; antimicrobial therapy usually resolves symptoms. While relapse may occur more frequently with single-dose therapy, late recurrence rates are the same and side effects are less than with multiple-dose therapy. Patients with relapsing infection or frequent recurrence are candidates for chronic prophylaxis with low-dose antimicrobial or prompt self-administered therapy.