Complex partial seizures of childhood onset: a clinical and encephalographic study1
Dudley S. Dinner, M.D.
Hans Lüders, M.D., Ph.D
A. David Rothner, M.D.
Gerald Erenberg, M.D.
Electroclinical manifestations of 30 patients with complex partial seizures (CPS) of childhood onset (<16 yr) were evaluated. Only patients with both clinical CPS and focal specific epileptiform activity shown on the electroencephalogram were selected. Febrile convulsions were present in 9 patients, suggesting that they play a significant role in the pathogenesis of CPS. All patients had a period of unresponsiveness with a blank stare and amnesia; 21 had an aura, including affective symptoms in 20. Hallucinations (5) and illusions (1) were infrequent. Only 16 had epileptiform discharges in their initial waking record, whereas in 8 others, epileptiform discharges were activated during sleep. Foci were predominantly unilateral (28) and mostly temporal (26); only 2 were bi-temporal, in contrast to the reported incidence of 31%–42% in adults, suggesting that the natural evolution of unilateral foci is to become bilateral.