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An overview of therapeutic drug monitoring principles1

Cleveland Clinic Journal of Medicine. 1984 April;51(2):241-254 | 10.3949/ccjm.51.2.241
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Abstract

Recent technological advances allow determination of anticonvulsant blood levels. Consequently, the principles of pharmacokinetics can be applied in managing patients with seizures. We review these principles as well as those of therapeutic drug monitoring for the control of antiepileptic drug levels.