Electrocardiographic changes during urography

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Electrocardiographic changes have been recorded in patients undergoing a variety of roentgenographic procedures. The wide spectrum of the effects of contrast media is well known. Reports of electrocardiographic changes following the injection of the contrast medium during a urogram are surprisingly few.1, 2 No large series using control groups has been reported. Berg et al2 recently examined 30 patients who had urograms and found electrocardiographic changes in a significant number of these patients but no controls were studied.

We examined 115 unselected, consecutive out-patients in the Department of Radiology.


None of the patients we examined had chest pain or shortness of breath either prior to or during the examination which was performed with the patient in the supine position.

All patients had a 12-lead electrocardiogram, including a 30-second rhythm strip (lead 2), before the examination. Following the electrocardiogram, all patients were monitored up to 4½ minutes after injection or infusion of the contrast medium, at which time another 12-lead electrocardiogram and a 30-second rhythm strip were taken. Two contrast media, Renografin-60* and Conray 400, and two dosage schedules were employed. Twenty-seven patients received 50 ml of Conray 400 as a bolus injection (Group A). Seven of these patients had a history of heart disease. Twenty-five patients, 10 of whom had a history of heart disease, were given a bolus injection of 50 ml of Renografin-60 (Group B). Thirteen patients received an infusion of Renografin 30% (150 ml Renografin-60 added to 150 ml sterile water; iodine content 14,376 mg/100 ml). . .



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