Article

Selective canine renal infarction

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Abstract

Several procedures using radiologically-guided catheter techniques for the production of selective infarcts of the dog’s kidney have been described.1–3 Doppman et al4 have reported their experience with a silicone rubber preparation injected through a non-balloon type catheter. This method involves the obstruction of the main renal artery and several branches and has been proposed as a mode of control of angiomatous malformations. It is an extension of the work in the control of spinal cord arteriovenous malformations.5 Previous experience in the production of experimental renal infarctions using balloon and non-balloon type catheters and Sephadex* has been reported.2, 3 We believe that the potentially rich collateral blood supply of the kidney, as well as the primary blood supply, must be obstructed.6 For this reason we have chosen a method using a particulate material calculated to obstruct the smallest vessels, rather than the method of Doppman et al. In this way we hope to prevent the development of a collateral blood supply through capsular vessels. Recently, a commercially available balloon type catheter suitable for selective injections was made available to us, and we report our experience in the development of a clinically useful nonsurgical ablation of the kidney which might be applied in patients with unilateral renal disease.

Method

Ten anesthetized dogs were studied on a nonsurvival basis. Preoperative and postoperative abdominal films were obtained, and the femoral artery was exposed and cannulated by a double lumen, balloon-tipped No. 7 Fr. Wooley catheter.* The tip of the catheter can be controlled and . . .


 

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