Congenital rubella syndrome with viral esophagitis

Author and Disclosure Information


THE congenital rubella syndrome is a multisystemic disorder with specific teratogenic anomalies and a variety of complications. This is a report on the ultrastructure of a viral hemorrhagic esophagitis, a hitherto not reported complication in congenital rubella syndrome.

Report of a case

The patient, a 15-month-old Caucasian female was born at full term to a woman who had had rubella at three weeks of gestation. After birth the patient was noted to have a patent ductus arteriosus, bilateral cataracts, left hip dysplasia, and microcephaly. The patent ductus arteriosus was repaired at 14 weeks. A cataract operation was performed when the patient was 14 months old. Two weeks later she was admitted to the Cleveland Clinic Hospital with a fever of unknown origin, anorexia and vomiting. Between the time of operation and the fever, the patient had been doing well. There was no history of convulsions or diarrhea. On physical examination the patient was moderately dehydrated, irritable, pale and distressed. The pupils reacted to light, the ears were normal, and the neck supple. The chest showed an old surgical scar; the lungs were clear to auscultation, and the heart sounds were normal. Laboratory studies revealed a blood sugar of 238 mg per 100 ml, and a blood urea nitrogen of 57 mg per 100 ml. The serum electrolytes were normal. The hemoglobin was 15.4 g per 100 ml. The hematocrit was 44 percent; the white cell count was 11,500 per cu mm with 34 percent lymphocytes, 61 percent polymorphonuclear cells and . . .



Next Article: