Etiology and Treatment of Gallbladder Disease
Since the discovery by Pasteur of the bacterial causes of many diseases and the rise of pathology from the days of Virchow, practically all disease entities have been regarded from these two standpoints, viz., patholgy and infection. The question may be raised whether it is not a mistake to attack the problem of gallbladder diseases with only these two points of view in mind. Instead of believing that the thyroid gland can originate a hyperplasia within itself, it is now known that hyperplasia is imposed upon the thyroid gland by factors from without. It is known also that peptic ulcer arises from influences originating outside itself. We now know that these diseases lie within the domain of pathologic physiology rather than in the field of pathologic morphology or of infection. Pathologic morphology and infection may be due to a primary pathologic physiology, which lays the foundation for their development, and this discussion of diseases of the liver and gallbladder is presented with this thesis in mind.
Any theory which attempts to explain the genesis of gall stones and of gallbladder disease must explain their distribution in nature and the sex and age incidence of the disease. It must account for the fact that gall stones occur more frequently in certain races, that they occur more frequently in women than in men, and further, that they occur more frequently in women who have borne children.
What is the distribution of gall stones in nature? Broadly speaking, this disease is less common. . .